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专利名称：5-[4-[2-(N-METHYL-N-(2-PYRIDYL)AMINO)ETHOXY]BENZYL]THIAZO…2,4-DIONE,MALEIC ACID SALT,HYDRATE ASPHARMACEUTICAL
发明人：BLACKLER, Paul, David, James,SmithKline
Beecham P,LEE, David, C.,SmithKline BeechamPharmaceuticals,SASSE, Michael,John,SmithKline Beecham Pharma.
申请号：EP9510.6申请日：19981214公开号：EP1040110A1公开日：20001004
摘要：A kind of hydrate 5- [4- [2- ((N-methyl-N- (2- pyridyl groups) amino) ethoxy]benzyl] thiazolidine -2, diketone, maleic acid salt, it is characterised in that it: (I) includesthat water range is from 0.4 to 2.5%w/w; (II) is provided comprising infrared spectral peakin 1749,1703,15,1623,1365 and 736 CM-1; And/or (III) provide X-ray (XRPD) patternsubstantially as shown in figure II and/or (IV) to provide Raman spectrum include toprovide the chemical shift comprising solid state nmr spectrum positioned at
3106,3069,3002,2961,1750,1718,1684,1385,1335,31060,31061,31062,31063 and 310 CM-1 and/or (IV) and be essentially in following table to provide I; The method for preparingthe compound, pharmaceutical composition contain such compound and the purposes ofthe compound or composition in medicine.
申请人：SMITHKLINE BEECHAM PLC
地址：New Horizons Court Brentford,Middlesex TW8 9EP GB
国籍：GB
代理机构：Rutter, Keith, Dr.
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