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PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF

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专利名称:PROCESSES AND INTERMEDIATES FOR THE

PREPARATION OF A PDE10 INHIBITOR

发明人:CUTSHALL, Neil S.,GAGE, Jennifer

Lynn,LITTLE, Thomas L.,LUKE, WayneDouglas,BROT, Elisabeth C.A.,JONAS,Marco,MCDERMOTT, MichaelJames,REINEKE, Karl E.

申请号:EP15785376.3申请日:20150424公开号:EP3137462A4公开日:20171227

摘要:The present invention is directed to an improved process for the preparation ofcompounds of Formula (II) and Formula (III), which are useful in the inhibition of PDE10. Inparticular, the present invention is directed to an improved process for the preparationof 1-(5-(4-chloro-3,5-dimethoxyphenyl)furan-2-yl)-2-ethoxy-2-(4-(5-methyl-1,3,4-thiadiazol-2-yl)phenyl)ethanone, which is useful in the inhibition of PDE10.

申请人:Omeros Corporation

地址:201 Elliott Avenue West Seattle, WA 98119 US

国籍:US

代理机构:Grünecker Patent- und Rechtsanwälte PartG mbB

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