专利内容由知识产权出版社提供
专利名称：Treatment For Rheumatoid Arthritis发明人：Alex Godwood,Fabio Magrini申请号：US14349706申请日：20121010
公开号：US20140335081A1公开日：20141113
摘要：Treatment of rheumatoid arthritis (RA) to provide clinical benefit in patients,including decrease in DAS28-CRP by more than 1.2 and/or improvement determined byACR20, ACR50 or ACR70, comprising administering therapeutic antibody mavrilimumab orother inhibitor targeted to Tyr-Leu-Asp-Phe-Gln motif of granulocyte/macrophagecolony stimulating factor receptor alpha (GM-CSFRα). Use of GM-CSFRα inhibitors such asmavrilimumab to enhance clinical benefit in RA patients receiving stable dose of DMARDs,particularly methotrexate.
申请人：Medimmune Limited
地址：Cambridge GB
国籍：GB
更多信息请下载全文后查看
